Fibrinolysis and proliferative endarteritis: two related processes in chronic infections? The model of the blood-borne pathogen Dirofilaria immitis. González-Miguel J, Morchón R, Siles-Lucas M, Simón F. PLoS One. 2015 Apr 13;10(4):e0124445. doi: 10.1371/journal.pone.0124445. The interaction between blood-borne pathogens and fibrinolysis…
The miRnome of Fasciola hepatica juveniles endorses the existence of a reduced set of highly divergent micro RNAs in parasitic flatworms. Fontenla S, Dell'Oca N, Smircich P, Tort JF, Siles-Lucas M. Int J Parasitol. 2015 Sep 30. pii: S0020-7519(15)00248-9. doi:10.1016/j.ijpara.2015.06.007.…
Serological Diagnosis and Follow-Up of Human Cystic Echinococcosis: A New Hope for the Future? Manzano-Román R, Sánchez-Ovejero C, Hernández-González A, Casulli A, Siles-Lucas M. Biomed Res Int. 2015;2015:428205. doi: 10.1155/2015/428205. Epub 2015 Oct 4. Review. Cystic echinococcosis (CE) is a…
Van Meulder F., Ratman D., Van Coppernolle S., Borloo J., Li R.W., Chiers K., Van den Broeck W., Claerebout E., Geldhof P., 2015. Analysis of the protective immune response following intramuscular vaccination of calves against the intestinal parasite Cooperia oncophora.…
Vlaminck J., Borloo J., Vercruysse J., Geldhof P., Claerebout E., 2015. Vaccination of calves against Cooperia oncophora with a double-domain activation-associated secreted protein reduces parasite egg output and pasture contamination. International Journal for Parasitology 45, 209-213; doi: 10.1016/j.ijpara.2014.11.001 Two vaccination…
Major advances have been made in identifying potential vaccine molecules for the control of liver fluke disease (fasciolosis) in livestock but the level of efficacy required for commercialization has yet to be reached.
Extracellular vesicles (EVs) released by parasites have important roles at the host-parasite interface. We have shown that adult Fasciola hepatica secretes at least two sub-populations of EVs that differ according to size, cargo molecules and site of release from the…
Jacqui Matthews is off to speak about PARAGONE at the BBSRC UK Veterinary Vaccinology Conference in Manchester: http://www.vetvaccnet.ac.uk/veterinary-vaccinology-network-conference-2016
The Fasciola hepatica genome: gene duplication and polymorphism reveals adaptation to the host environment and the capacity for rapid evolution
Fasciola hepatica mucin-encoding gene: expression, variability and its potential relevance in host–parasite relationship MARTÍN CANCELA, GUILHERME B. SANTOS, CARLOS CARMONA, HENRIQUE B. FERREIRA, JOSÉ FRANCISCO TORT and ARNALDO ZAHA1 Received 2 June 2015; revised 16 July 2015; accepted 1 August 2015…